4 décadas de estudos sobre a Cannabis e doenças cardíacas
DOENÇA CARDÍACA / CARDIOVASCULARES & Estudos concluídos da Cannabis nestas 4 décadas.
Undated - News - Cardiovascular Effects of Cannabis.
1973 - Letter ~ Effects of cannabis roots on the heart.
1975 - Study ~ Intravenous delta9-Tetrahydrocannabinol: Effects of ventilatory control and cardiovascular dynamics.
1976 - Study ~ The Effects of Delta-9-Tetrahydrocannabinol (Cannabis) on Cardiac Performance with and without Beta Blockade.
1977 - Study ~ Short-term effects of smoked marihuana on left ventricular function in man.
1977 - Study ~ Propranolol Effects on Acute Marihuana Intoxication in Man.
1980 - Study ~ Cannabinoids. II. Cardiovascular Effects.
1981 - Study ~ The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys.
1986 - Study ~ Effects of acute marijuana smoking in post-menopausal women.
1989 - Study ~ The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation.
1992 - Study - Changes in middle cerebral artery velocity after marijuana.
1995 - Study ~ Development of HU-211 as a neuroprotectant for ischemic brain damage.
1995 - Study ~ Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide.
1997 - Study ~ Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors.
2000 - Study ~ Cardiovascular effects of endocannabinoids--the plot thickens.
2000 - Study ~ Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine.
2001 - Study ~ Endogenous cannabinoids mediate hypotension after experimental myocardial infarction.
2001 - Study ~ Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries.
2001 - Study ~ Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts.
2001 - Study ~ Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors.
2002 - Study ~ Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats.
2002 - Study ~ Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts.
2002 - Study ~ Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and platelet activation.
2002 - Study ~ Activation of cannabinoid receptors decreases the area of ischemic myocardial necrosis.
2002 - Study ~ Anandamide and R-(+)-methanandamide prevent development of ischemic and reperfusion arrhythmia in rats by stimulation of CB2-receptors.
2002 - Study ~ Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors.
2002 - Study ~ Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism.
2003 - Study ~ Endocannabinoids protect the rat isolated heart against ischaemia.
2003 - Study ~ Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery.
2003 - Study ~ Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN.
2003 - Study ~ A new endothelial target for cannabinoids.
2003 - Study ~ Endocannabinoids as mediators in the heart: a potential target for therapy of remodelling after myocardial infarction?
2003 - News - Cannabinoids prevented the development of heart failure in animal study.
2004 - Study ~ Endocannabinoids Acting at Cannabinoid-1 Receptors Regulate Cardiovascular Function in Hypertension.
2004 - Study ~ Vasorelaxant activities of the putative endocannabinoid virodhamine in rat isolated small mesenteric artery.
2004 - Study ~ The complexities of the cardiovascular actions of cannabinoids.
2005 - Study - Cardiovascular pharmacology of cannabinoids.
2005 - Study ~ Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia–reperfusion by a novel cannabinoid mechanism.
2005 - Study ~ Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats.
2005 - Study ~ The cardiovascular actions of anandamide: more targets?
2005 - Study ~ Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: role of cannabinoid and vanilloid receptors.
2005 - Study ~ Cardiac and vascular effects of cannabinoids: toward a therapeutic use?
2005 - Study ~ Influence of Anandamide, the Endogenous Agonist of Cannabinoid Receptors on the Circulatory System.
2005 - News - Marijuana Chemical Fights Hardened Arteries.
2005 - News - Medical marijuana: study shows that THC slows atherosclerosis.
2005 - News ~ Medical biology: Marijuana and the heart.
2005 - News ~ Medical marijuana: study shows that THC slows atherosclerosis.
2005 - News ~ Cannabis chemical 'helps heart'.
2006 - Study ~ Illicit Drug Use in Young Adults and Subsequent Decline in General Health: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.
2006 - Study ~ Signaling pathways involved in the cardioprotective effects of cannabinoids.
2006 - Study - The endogenous cardiac cannabinoid system: a new protective mechanism.
2006 - Study - Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production.
2006 - Study - Does Cannabis Hold the Key to Treating Cardiometabolic Disease?
2006 - Study - Marijuana use, diet, body mass index, and cardiovascular risk factors.
2006 - News - THC protects heart cells in the case of lowered oxygen supply.
2006 - News ~ Cannabis use not associated with risk factors for diseases of heart and circulation.
2006 - News - Cannabinoid Offers Cardioprotection.
2006 - News - Heavy Cannabis Use Not Independently Associated With Cardiovascular Risks.
2007 - Study - Cannabinoids and cardiovascular disease.
2007 - Study - Cannabinoids as therapeutic agents in cardiovascular disease.
2007 - Study - The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol.
2007 - Study - Cannabidiol protects against myocardial ischemic reperfusion injury.
2007 - Study - Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions.
2007 - Study ~ Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
2007 - Study ~ The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects.
2007 - Study ~ Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats.
2007 - Study ~ Endocannabinoids and the haematological system.
2007 - Study ~ Cannabinoids and cardiovascular disease: a tale of passions and illusions.
2007 - Study ~ GPR55 and the vascular receptors for cannabinoids.
2007 - Study ~ Cannabidiol , a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury.
2007 - Study ~ Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats.
2007 - Study ~ Effect of dietary hempseed intake on cardiac ischemia-reperfusion injury.
2007 - Study ~ Cannabinoids and cardiovascular disease: the outlook for clinical treatments.
2008 - Study - Function of cannabinoids in heart failure.
2008 - Study ~ The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.
2008 - Study ~ Cannabinoid receptors in acute and chronic complications of atherosclerosis.
2008 - Study ~ Endocannabinoids and Liver Disease. V. Endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis.
2008 - Study ~ CB1 Cannabinoid Receptor Inhibition: Promising Approach for Heart Failure?
2008 - Study ~ 'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors.
2008 - Study ~ Modulation of the Endocannabinoid System in Cardiovascular Disease.
2008 - Study ~ Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats.
2008 - Study ~ Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning.
2008 - Study ~ Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product.
2008 - Study ~ Endocannabinoids, blood pressure and the human heart.
2008 - Study ~ Function of cannabinoids in heart failure.
2008 - Study ~ The endocannabinoid system: an osteopathic perspective.
2008 - Study ~ Dexanabinol prevents development of vasospasm in the rat femoral artery model.
2008 - News ~ Rimonabant doesn't reduce heart risk.
2008 - News - Cannabis use not associated with risk factors for diseases of heart and circulation.
2008 - News - Research Shows That Hemp Seed Can Help Fight Heart Disease.
2009 - Study - Cannabinoids and atherosclerosis.
2009 - Study ~ Endocannabinoids and cardiac contractile function: pathophysiological implications.
2009 - Study ~ Endocannabinoids and cannabinoid analogues block cardiac hKv1.5 channels in a cannabinoid receptor-independent manner.
2009 - Study ~ Endocannabinoids and the Heart.
2009 - Study ~ The emerging role of the endocannabinoid system in cardiovascular disease.
2009 - Study ~ Endocannabinoid signalling as an anti-inflammatory therapeutic target in atherosclerosis: does it work?
2009 - Study ~ CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages.
2009 - Study ~ Time-dependent vascular actions of cannabidiol in the rat aorta.
2009 - Study ~ Endocannabinoids and cardiovascular prevention: real progress?
2009 - Study ~ CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion.
2010 - Study ~ Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.
2010 - Study ~ The cardiac and haemostatic effects of dietary hempseed.
2010 - Study ~ Endogenous cannabinoid signaling is essential for stress adaptation.
2010 - Study ~ Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation.
2010 - Study ~ Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.
2010 - Study ~ Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure.
2010 - Study ~ Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery.
2010 - Patent ~ US Patent Application 20100158973 - THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS.
2010 - News ~ Lab Notes: Pot Has Benefits for Diabetic Hearts.
2010 - News ~ Inhaled Incense "K2" May Cause Heart Damage.
2010 - News ~ Cannabidiol (CBD) as an Anti-Arrhythmic – the Role of the CB1 Receptors.
2010 - News ~ Pot Compound Mitigates Diabetic Cardiomyopathy.
2011 - Study ~ The potential for clinical use of cannabinoids in treatment of cardiovascular diseases.
2011 - Study ~ Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities.
2011 - Study ~ Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.
2011 - Study ~ Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors.
2011 - Study ~ Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease.
2011 - Study ~ Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice.
2011 - Study ~ G1359A polymorphism in the cannabinoid receptor-1 gene is associated with coronary artery disease in the Chinese Han population.
2011 - Study ~ The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia.
2011 - Study ~ Win 55,212-2 reduces cardiac ischaemia-reperfusion injury in zucker diabetic fatty rats: role of cb2 receptors and cardiac inos/enos expression.
2011 - Study ~ Cannabinoid-2 Receptor Activation Protects against Infarct and Ischemia/Reperfusion Heart Injury.
2011 - Study ~ Endocannabinoids and the cardiovascular response to stress.
2011 - Study ~ Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation.
2011 - Study ~ Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress.
2011 - Study ~ The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits.
2011 - Study ~ Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury.
2011 - Study ~ Cannabidiol (CBD) as an Anti-Arrhythmic.
2011 - News ~ Marijuana Compounds Hold Promise In Treatment Of Cardiovascular Diseases.
2011 - News ~ Hemp Fiber Cereal.
2012 - Study ~ Cannabinoids and atherosclerotic coronary heart disease.
2012 - Study ~ Cannabinoid 1 (CB1) receptor mediates WIN55, 212-2 induced hypothermia and improved survival in a rat post-cardiac arrest model.
2012 - Study ~ Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors.
2012 - Study ~ Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation.
2012 - Study ~ Subjective, cognitive and cardiovascular dose-effect profile of nabilone and dronabinol in marijuana smokers.
2012 - Study ~ Cannabinoid receptor CB2 protects against balloon-induced neointima formation.
2012 - Study ~ Targeting cannabinoid receptor CB(2 ) in cardiovascular disorders: promises and controversies.
2012 - Study ~ Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation.
2012 - Study ~ Targeting cannabinoid receptor CB(2 ) in cardiovascular disorders: promises and controversies.
FONTE: http://www.calgarycmmc.com/heartdisease.htm
